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A. How does it work?

(Why What)

Adulthood

1. Androgen transport mechanism

Genes typically strongly impact sex hormone production in men and regulate its levels as the body matures as well as during adulthood. Similarly, the way cells will respond to sex hormones is also predetermined by a person’s genetic makeup. Indeed, a study has shown that the passive diffusion of the androgen hormone in the blood and its effective associations with receptors relies on a protein called the sex hormone-binding globulin (SHBG). Heredity accounts for up to 50% of the SHBG’s strength, while numerous genes – PRMT6, GCKR, ZBTB10, JMJD1C, SLCO1B1, NR2F2, ZNF652, TDGF3, LHCGR, BAIAP2L1 and UGT2B15- play a role in regulating SHBG production.

2. Metabolic pathway

In the male organism, the health of the gut microbiota impacts the metabolism as well as hormonal production.

3. Good nutrition

A balanced diet is particularly important to the male adult body given that nutrients regulate the endocrines; combined with the adrenal glands and testicles, these play an essential role in androgen production.

4. Antioxidants

ROS (Reactive Oxygen Species) and RNS (Reactive Nitrogen Species) free radicals constitute a significant threat to cells present in the human body. Generated at the final stages of the metabolic process, their accumulation results in oxidative stress, which can harm protein, lipids, as well as DNA present in body cells, which ultimately can lead to their deterioration and a disturbance in the normal functioning of the organism. Such a development can bring about acute conditions caused by dysfunctions in both hormonal and reproductive systems.

B. In the absence of the elements

listed in A,

the following may occur:

1. Influence on endocrine system

Adults with genetic disorders may suffer a range of conditions related to the endocrine system, which produces sex hormones.

2. Dysbiosis

In the gut, there are two main types of flora: while one is beneficial, the other is harmful. The gravity of bacterial imbalances is such that these alone can upset the entire organism, including the endocrinal system, which is typically triggered by its chronic inflammation. Furthermore, a disruption of the endocrines has been linked with dysfunctions linked to the male sex hormone, androgen, resulting in either its excess or its deficiency.

3. Endocrine system disorder

Regardless of a person’s age, an unhealthy diet always negatively impacts the organism. In adult men, bad eating habits can trigger sex hormone imbalances, pancreatic dysfunction, a low bone density, fat deposition, and hinder cognitive functions.

4. Androgen and reproductive disorders

Long-term chronic inflammation is also responsible for dysfunctions in the endocrine gland, which can negatively impact androgen levels.

C. Towards developing effective solutions

1. Further research

Several medical studies evidence the fact that a range of fatal illnesses are caused by the overlap between recessive genes and the androgen function. Currently, however, further research needs to be conducted to develop potential treatment options in compliance with medical practice.

2. Providing prebiotics and probiotics

Prebiotics and non-digestible polysaccharides can harmonize and even out gut bacteria to optimize and prevent imbalances in the gut microbiota. Prebiotics should not be confused with probiotics, live bacteria of which the properties are beneficial to the digestive and metabolic systems, as well as the gut flora. Hence, a balanced gut bacterium is essential to adult men’s health.

3. Nourishing foods

Nutrition is especially important to hormonal production in adults. Nutrients that are vital to sex hormone production are:

Essential nutritions for balancing androgen level

 

3.1 Calciferol

Calciferol functions like a hormone, and is commonly found in sea fish, eggs, and milk. It has been found that in men, a deficiency in protein may lead to lower sex hormonal levels, whereas calcium boron increases them,

3.2 Zinc

Meat, eggs, and soybeans, cereals, and oyster are rich in zinc, an important chemical element for the well-functioning of the body. It is also known to be a male sex hormone booster. A zinc deficiency, however, has been associated with low androgen levels. Therefore, a prescription for a zinc supplement can rectify this problem.

3.3 Phenol

In addition to strengthening the antioxidative system, phenol facilitates testosterone production, a male sex hormone responsible for several male traits. Phenol also boosts male fertility, by increasing both the quantity and quality of sperm.

4. Providing active substances that prevent free radicals

The antioxidant defense, which serves the critical function of shielding the body against harmful free radicals, can be enhanced by means of the adoption of a nutritive diet, rich in antioxidants. Indeed, antioxidants prevent premature cellular aging and irregular hormonal activity.

Antioxidants

There are in total two different types of antioxidants :

1. Enzymatic antioxidants

Enzymatic antioxidants, on the one hand, transform themselves into enzymes such as superoxide dismutases (SODs), catalase, and others that form the glutathione system.

2. Non Enzymatic antioxidants

Non-enzymatic antioxidants consist of the following: ascorbic acid (i.e., vitamin C), glutathione, melatonin, tocopherols and tocotrienols (i.e., Vitamin E), as well as carotenoids, flavonoids and uric acid.

Consuming foods on a regular basis that are rich in antioxidants will facilitate the elimination of excessive of free radicals that typically harm the DNA and cell structures.

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