A. How does it work?
The menopause is an age-related condition characterized by a disruption of the menstrual cycle. Inherited genes not only have an impact sex hormone, but also, significantly determines the characteristics of the menopausal transition, which means that it can vary greatly from one woman to another. Researchers have discovered that instances of early menopause are correlated with stroke and atherosclerosis, while late menopause increases the likelihood of breast cancer. Recently, a study discovered which specific chromosome is linked with the early onset of the menopause.
2. The maintenance of gut microbiota
In the long run, the sustenance of a balanced gut microbiota yields significant benefits to the metabolic system, which consists of the chemical process that absorb and breakdown ingested nutrients, such as protein, lipids, carbohydrates, and nucleic acid.
In a well-functioning organism, estrogen is absorbed by the liver as it circulates in the blood stream. The encounter between the estrogen hormone and glucuronic acid -which eliminates toxins in the liver-, however, typically generates a large and complex composite, which is discharged via execration as it cannot be absorbed by the gastrointestinal wall.
ROS (Reactive Oxygen Species) and RNS (Reactive Nitrogen Species) free radicals constitute a significant threat to cells present in the human body. Generated at the final stages of the metabolic process, their accumulation results in oxidative stress, which can harm protein, lipids, as well as DNA present in body cells, which ultimately can lead to their deterioration and a disturbance in the normal functioning of the organism. Such a development can bring about acute conditions caused by dysfunctions in both hormonal and reproductive systems.
B. In the absence of the elements
listed in A,
the following may occur :
1. Genetic abnormalities caused by anomalies in genes
Genetics are also involved in the menopausal transition and define its characteristics. Premature menopause makes women at risk of stroke and coronary artery disease, while late menopause has been correlated with breast cancer.
2. Estrogen imbalance
The gravity of bacterial imbalances is such that these alone can upset the entire organism, including visceral organs and the endocrinal system, typically triggering chronic inflammations to digestion problems. Furthermore, a disruption of the endocrines has been linked with estrogen dominance and deficiency.
3. Endocrine glands malfunctions
Malnutrition and hyperalimentation can alter the endocrine system and result in estrogen dominance and deficiency.
4. Abnormal level of sex hormones
Long-term chronic inflammation is also responsible for dysfunctions in the endocrine gland, which can negatively impact androgen levels. The deteriorating condition of the ageing body further impedes effectiveness of treatments and recovery from injury and illness.
C. Developing effective solutions
1. Further research
Several medical studies suggest that several fatal illnesses -including breast cancer- are caused by the overlap between recessive genes and the androgen function. Currently, however, further research needs to be conducted to develop potential treatment options in compliance with medical practice.
2. Regulating microorganisms in gastro-intestinal tract
Prebiotics can harmonize and even out gut bacteria to optimize and prevent imbalances in the gut microbiota. This balance is notably crucial to the well-functioning of the digestive and endocrinal systems. An disruption in regular activity can easily trigger an estrogen imbalance that can significantly harm seniors.
3. Sufficiently nutritious dietary intake
Nutrition in childhood and teenagehood is especially important to hormonal production. Nutrients that are vital to sex hormone production include DIM (Diindolylmethane), Calcium D-Glucarate, Magnesium, and Isoflavones, which can be easily found in different members of the pea and bean species.
4. Providing active substances that prevent free radicals
Because of pollution, ultraviolet radiation and the daily usage of synthetic chemicals, the environment is increasingly toxic, and causing an unprecedented amount of harm to human bodies. Hence, developing and sustaining a strong defense system against free radicals is critical. An effective defense can, for example, protect against chronic inflammatory cellular and chromosome damage, which can affect the hormonal system’s proper functioning in the body.
There are in total two different types of antioxidants :
1. Enzymatic antioxidants
Enzymatic antioxidants, on the one hand, transform themselves into enzymes such as superoxide dismutases (SODs), catalase, and others that form the glutathione system.
2. Non Enzymatic antioxidants
Non-enzymatic antioxidants consist of the following: ascorbic acid (i.e., vitamin C), glutathione, melatonin, tocopherols and tocotrienols (i.e., Vitamin E), as well as carotenoids, flavonoids and uric acid.
Consuming foods on a regular basis that are rich in antioxidants will facilitate the elimination of excessive of free radicals that typically harm the DNA and cell structures.